Overview

We´re presently interested in these lines of research:

1) The in silico and in vivo validation of our community assembly conceptual framework.

2) The isolation and characterization of a representative rhizosphere community and its associated viruses.

3) The development of tools to monitor and dissect biotic interactions in the rhizosphere.

4) The robotization of highthrouput culturomics and NGS pipelines.

5) The development of Oxford Nanopore-based approaches in microbial and environmental genomics.

Selected recent publications:

Talavera-Marcos, S., Parras-Moltó, M., Aguirre de Cárcer, D. (2023) Lverageing phylogenetic signal to unravel microbiome function and assembly rules. Comput Struct Biotechnol J. 21, 5165-5173.

Gallego, R., Jacobs-Palmer, E., Cribari, K., Kelly, R. P. (2020). Environmental DNA metabarcoding reveals winners and losers of global change in coastal waters. Proceedings of the Royal Society B, 287(1940), 20202424.

Kelly, R. P., Shelton, A. O., & Gallego, R. (2019). Understanding PCR processes to draw meaningful conclusions from environmental DNA studies. Scientific reports, 9(1), 1-14.

Parras-Moltó M, Aguirre de Cárcer D (2021) A comprehensive human minimal gut metagenome extends the host´s metabolic potential. Microbial Genomics. https://doi.org/10.1099/mgen.0.000466

Parras-Moltó M, Aguirre de Cárcer D (2021) Assessment of phylo-functional coherence along the bacterial phylogeny and taxonomy. Scientific Reports 11, 8299.

Aguirre de Cárcer D (2020) Experimental and computational approaches to unravel community assembly. Comput Struct Biotechnol J. 18, 4071-4081.

Aguirre de Cárcer D (2019) A conceptual framework for the phylogenetically-constrained assembly of microbial communities. Microbiome. 7, 142.

Grants:

-ConsolidateME_GENOMICS. AEI: CNS2022-135371 01/07/2023 - 30/06/2025 [PI:DAC]

-TopDownMicrobiomes. AEI: TED2021-130616B-100. 01/01/2023 - 31/12/2024 [PI:DAC]

-NANOBARCODING. UAM: BIOUAM03-2033. 28/10/2022 - 27/10/2023 [PI: RG]

-RIZOVIR. UAM: BIOUAM01-2021. 21/10/2021 - 20/10/2022 [PI: AR]

-PHYLOASSEMBLY. AEI: PID2019-108797RB-I00. 06/01/2020 - 05/31/2023 [PI: DAC]

-SHORTCUT. AEI: EIN2019-103289. 01/01/2019 - 02/04/2020 [PI: DAC]

-PANMICROBIOMA. MINECO: BIO2016-80101-R 30/12/2016 - 12/31/2020 [PI: DAC]

-IDMS. MINECO: BFU2013-50537-EXP. 09/01/2014 - 08/30/2015 [PI: DAC]

-COOLVIROMES. EU-FP7: PIIF-GA-2012-328287. 07/01/2013 - 09/08/2015 [PI: DAC]